Explain the mechanism by which human immunodeficiency virus (HIV) enters a host cell

What will be an ideal response?


Human immunodeficiency virus (HIV) infects cells bearing CD4 molecules on their surface. These include TH1 and TH2 cells, macrophages, and dendritic cells. CD4 acts as a receptor involved in binding the gp120 envelope glycoprotein of HIV. A co-receptor is also required for virus entry. Two are used by HIV: the chemokine receptors CCR5 and CXCR4. CCR5 is expressed on all CD4+ cells, whereas CXCR4 is restricted to T cells. After binding to the co-receptor, another viral envelope glycoprotein, gp41, facilitates fusion between the host cell's plasma membrane and viral envelope with the release of viral components into the cytoplasm.

Health & Biomechanics

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The Hammond Company purchased 8 3/4 acres for a housing project. One and a half acres were set aside for a park. a. How many acres are available for housing? b. How many 1/4 acre parcels of land can be sold after the land for the park is set aside?

A) (a) 7 1/4 acres; (b) 33 parcels B) (a) 8 1/4 acres; (b) 33 parcels C) (a) 8 1/4 acres; (b) 29 parcels D) (a) 7 1/4 acres; (b) 29 parcels E) (a) 8 acres; (b) 32 parcels

Health & Biomechanics

You can pick up germs by touching doorknobs, counters, and other objects.

Answer the following statement true (T) or false (F)

Health & Biomechanics

Inflammation of the urinary bladder:

a. cytitis b. cystitis c. sistitis

Health & Biomechanics

Inflammation and swelling of soft tissue around a nail: par__________

Fill in the blank(s) with correct word

Health & Biomechanics