A nurse provides teaching for a 25-year-old patient who will receive mitoxantrone (Novantrone) for worsening relapsing-remitting multiple sclerosis. Which statement by the patient indicates a need for further teaching?
a. "I may experience cardiac side effects several years after receiving this drug."
b. "I should report fever, chills, cough, and hoarseness immediately."
c. "I will need an infusion of this medication once weekly."
d. "I will need a liver function test and a pregnancy test before each dose."
ANS: C
Mitoxantrone is given as an infusion once every 3 months. Cardiac side effects may become apparent during treatment or up to years after discontinuation of the drug. Fever, chills, cough, and hoarseness are signs of infection and should be reported immediately. LFTs and a pregnancy test should be done before each infusion.
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