Imagine that you could microinject cytochrome c into the cytosol of both wild-type cells and cells that were lacking both Bax and Bak, which are apoptosis-promoting members of the Bcl2 family of proteins
Would you expect one, both, or neither of the cell lines to undergo apoptosis? Explain your reasoning.
The presence or absence of Bak and Bax would not affect whether a microinjection of cytochrome c would promote apoptosis, because Bax and Bak act upstream of cytochrome c by promoting its release from mitochondria. By promoting the formation of the apoptosome and the activation of procaspases, microinjection of cytochrome c bypasses the need for Bax or Bak in promoting apoptosis.
You might also like to view...
A patient suspected of having tuberculosis has been admitted to the hospital. Which one of the following is not appropriate?
A) droplet precautions B) source isolation C) standard precautions D) use of a type N95 respirator by healthcare professional who are caring for the patient
What part of the E. coli T4 phage attaches to the host cell receptors?
A. Capsid fragments around the nucleic acid B. Protein fibers at the end of the phage tail C. Pili of the envelope D. Spikes of the envelope
Adding acetyl groups makes genes accessible
to transcription by a. increasing the pH of the cell. b. making histones loosen their grip on the DNA molecule. c. modifying the nucleotides of the promoter region of the DNA molecule. d. enhancing the activity of RNA polymerase. e. enhancing the development of a DNA-RNA hybrid
How is the trachea like xylem?
a. Both conduct fluids b. Both are structurally reinforced to withstand negative pressure c. Both are composed of cells with strong cell walls d. Both provide structural support to the organism