An analysis of aborted tissues reveals that the fetus had an aneuploid condition. The nurse asks the mother if her menstrual periods are generally regular. What is the rationale for this question?

1. Many spontaneous abortions occur before the mother is aware she is pregnant.
2. Menstrual irregularities signal hormone alterations that may cause aneuploidy.
3. Spontaneous abortion often "resets" a woman's hormonal cycle, making periods more regular.
4. Aneuploidy's greatest effects are on the secondary sexual characteristics.


1
Rationale 1: Aneuploidy is a leading cause of spontaneous abortions, often before the woman is aware she is pregnant. Irregularity in a normally regular menstrual cycle may indicate that the woman aborted without knowing she was pregnant.
Rationale 2: There is no indication that hormone alterations or menstrual irregularities cause aneuploidy.
Rationale 3: There is no evidence that this is true.
Rationale 4: Aneuploidy in the fetus would not cause a change in the secondary sexual characteristics of the mother.

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