A patient has been taking levothyroxine for several years and reports that "for the past 2 weeks, the drug doesn't seem to work as well as before." What will the nurse do?
a. Ask the patient when the prescription was last refilled.
b. Expect the patient to have an elevated temperature and tachycardia.
c. Suggest that the patient begin taking calcium supplements.
d. Tell the patient to try taking the medication with food.
ANS: A
Not all levothyroxine preparations have the same drug bioavailability; therefore, if a patient is experiencing differing effects, the pharmacist may have switched brands. Asking a patient about a recent refill may help to explain why the drug has different effects. An elevated temperature and tachycardia would be signs of toxicity, not of a decrease in effectiveness. Calcium supplements and food would only interfere with absorption and further reduce the drug's effectiveness.
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