Which of the following changes associated with aging contributes to heart failure development in older adults? Select all that apply
A)
Increased incidence of mitral stenosis
B)
Sludge buildup in the kidneys
C)
Elevated diastolic BP
D)
Increased vascular stiffness
E)
Inflammation in the joints due to arthritis
Ans:
C, D
Feedback:
Changes with aging contribute to the development of HF in older adults. First is reduced responsiveness to β-adrenergic stimulation. Second is increased vascular stiffness that contributes to ventricular hypertrophy. Third, the heart itself becomes less compliant with age. Fourth relates to altered myocardial metabolism at the level of the mitochondria. Older adults usually develop aortic stenosis and mitral regurgitation. Kidney stones do not contribute to HF. Increase in diastolic pressure compromises LV filling leading to increases in pressures predisposing to HF. Arthritis is not associated with heart failure.
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