A client's primary care provider has added 20 mg of Lasix (furosemide) to his medication regimen to treat his primary hypertension. How does this agent achieve its therapeutic effect?
A) By decreasing vascular volume by increasing sodium and water excretion
B) By blocking the release of antidiuretic hormone from the posterior pituitary
C) By inhibiting the conversion of angiotensin I to angiotensin II
D) By inhibiting the movement of calcium into arterial smooth muscle cells
Ans: A
Feedback:
Diuretics lower blood pressure initially by decreasing vascular volume (by suppressing renal reabsorption of sodium and increasing sodium and water excretion) and cardiac output. Angiotensin-converting enzyme (ACE) inhibitors block the conversion of angiotensin I, and calcium channels blockers inhibit the movement of calcium into arterial smooth muscle. Common antihypertensives do not act directly on the pituitary.
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