The nurse knows that a patient may develop sensorineural hearing loss as a result of ototoxic drugs. Which patient would be at highest risk for this type of hearing deficit?
1. A patient with methicillin-resistant Staphylococcus aureus (MRSA) on high doses of vancomycin (Vancocin)
2. A patient on low-dose aspirin to prevent stroke
3. A patient on steroids (Prednisone) for chronic spondylolisthesis
4. A patient using atorvastatin (Lipitor) to prevent heart disease and stroke
1
Rationale 1: Ototoxic drugs damage the hair cells of the organ of Corti, resulting in sensorineural hearing loss. Vancomycin is ototoxic.
Rationale 2: Aspirin is ototoxic, but low doses are not high risk.
Rationale 3: Steroids are not ototoxic.
Rationale 4: Atorvastatin is not ototoxic.
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