The genome has more influence on the function of cells in different organs than does the proteome.
Answer the following statement true (T) or false (F)
False
Clarify Question
• What is the key concept addressed by the question?
o This question is asking whether the proteome or the genome have more influence on the function of cells in different organs.
• What type of thinking is required?
o You are being asked to take what you already know and use, or apply, it to an analysis of the proteome and genome.
• What key words does the question contain and what do they mean?
o The proteome is the complete protein composition of a cell or organism. The genome is all of the genetic material in a cell.
Gather Content
• What do you already know about genomes and proteomes? How does it relate to the question?
o Recall that all cells within an organism contain the same genome. By contrast, the proteome differs from cell to cell.
Consider Possibilities
• What other information is related to the question? Which information is most useful?
o Recall that cell types can be different from each other because they often produce different proteins and in different amounts than each other. Additionally, different forms of proteins can be formed in different cells, and the proteins can be modified differently in different cells.
Choose Answer
• Given what you now know, what information and/or problem solving approach is most likely to produce the correct answer?
o The logic above suggests that proteomes have more influence on the function of cells in different organs than the genome does, so the correct answer is "False."
Reflect on Process
• Did your problem-solving process lead you to the correct answer? If not, where did the process break down or lead you astray? How can you revise your approach to produce a more desirable result?
o This question asked you to consider whether the proteome or the genome has more influence in creating different cell types. Answering this question correctly depended on your ability to use the definitions of proteome and genome in a new situation. If you got the correct answer, great job! If you got an incorrect answer, where did the process break down? Did you remember the difference between a proteome and genome? Did you remember how the proteome is responsible for different cell types within the same organism?
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