The expectant mother asks the nurse how CMV is diagnosed in infants. The best answer by the nurse would be:
a. "Check for the presence of IgM CMV antibodies in cord blood, which identifies congenitally infected infants; there is another test for detecting antibodies in the baby's blood."
b. "Inspect for the presence of symptoms characteristic of this disease."
c. "Conduct a test on the fluids of the eye, which are carefully collected on a swab and placed in a special tube."
d. "Inspect for the effects of the IgM CMV antibodies, which are evident in special tissue tests done in utero or shortly after birth."
A
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A Correct. CMV is diagnosed in infants by looking for the presence of IgM CMV antibodies in cord blood, which identifies congenitally infected infants. There is another test for detecting antibodies in the baby's blood.
B Incorrect. CMV is largely asymptomatic, and can only be diagnosed using appropriate tests on infants.
C Incorrect. Testing the fluids of the eye will not identify the presence of CMV.
D Incorrect. The effects of the IgM CMV antibodies are not visually available for inspection, but only appear under the microscope using a polymerase chain reaction to detect the presence of CMV DNA in tissues.
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