In an island population, the frequencies of the three MN blood types are given here:
M: 550
MN: 725
N: 225
a. Calculate the allele frequency of M and N.
b. Assuming random mating, what are the expected frequencies for each blood type?
c. Use chi-square analysis to test your hypothesis that mating is random for this population.
a. p = f (M) = [2(550 ) + 725]/3000 = 0.608
q = f (N) = [2(225 ) + 725]/3000 = 0.392
b. f (M) = (0.608)2(1500 ) = 555
f (MN) = (2 )(0.608 )(0.392 )(1500 ) = 715
f (N) = (0.392 )2(1500 ) = 230
c. 2 = [(550 – 555)2/555] + [(725 –715)2/715] + [(225 – 230 ) 2/230] = 0.2936
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