An older patient is surprised to learn of the diagnosis of rheumatoid arthritis. What can the nurse explain to the patient about this disorder? Select all that apply.
1. Antibodies form against the person's own IgG.
2. The onset of the disorder is slower in older adults.
3. It is a delayed hypersensitivity response to an antigen.
4. There can be abnormalities in both B and T immunity cells.
5. Inflammatory process is stimulated by T cells and destroys articular cartilage.
1. Antibodies form against the person's own IgG.
5. Inflammatory process is stimulated by T cells and destroys articular cartilage.
Explanation: 1. Rheumatoid arthritis is a type III hypersensitivity response where antibodies form against the person's own IgG causing the complex to be identified as foreign.
2. Type IV hypersensitivity responses are slower in older adults.
3. Type IV hypersensitivity responses are delayed responses to an antigen.
4. Abnormalities in both B and T cells have been seen in people with multiple sclerosis which is theorized to be a type IV hypersensitivity response.
5. In rheumatoid arthritis, the inflammatory process is stimulated by infiltrating T cells and gradually destroys articular cartilage.
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