What advantage would using human artificial chromosomes (HAC) for gene therapy have over introducing genes into the genome randomly?
What will be an ideal response?
It would avoid problems such as inserting the gene into a region that has suppressed expression or interrupting a gene whose loss of function could result in cancer.
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Suppose you take a cell from an adult cow and attempt to use it to produce a clone of that cow. If for
some reason telomerase is not functioning in that cell or in any cell that comes from it, what will you expect to happen with your clone?
a. The cell will never be able to divide at all. b. When the clone grows up, it will most likely have cancer. c. The cell may divide, but after a certain number of divisions, cell division will stop. d. The lack of telomerase should have no effect on the clone. e. When the clone grows up, it will most likely be sterile.
Name the membrane-enclosed compartments in a eukaryotic cell where each of the functions listed below takes place
A. photosynthesis B. transcription C. oxidative phosphorylation D. modification of secreted proteins E. steroid hormone synthesis F. degradation of worn-out organelles G. new membrane synthesis H. breakdown of lipids and toxic molecules
Migration of a random few individuals from one population to a new area to establish a new population is an example of ____
A. Bottleneck effect B. Mutation C. Founder effect D. Selection
A probe can help to find a sequence of interest in a genomic library because ________
a. the probe ruptures the cells and releases their DNA b. some of the cells from each colony will bind to the probe c. the sequence of interest is radioactive and will darken X-ray film d. the probe is labeled and will hybridize to the sequence