Which of the following statements about mesangial cells within the glomerulus is accurate? Select all that apply. Mesangial cells
A) cover the entire amount of endothelial cells contained within the capillaries.
B) have phagocytic properties that remove macromolecular materials.
C) exhibit vasodilator properties to assist with increase in blood flow in times of stress.
D) enlarge (hyperplasia) in response to glomerular diseases.
E) are coiled and drain Bowman capsule.
Ans:
B, D
Feedback:
Mesangial cells possess phagocytic properties and remove macromolecular materials that enter the intercapillary spaces. Mesangial cells also exhibit contractile properties in response to neurohumoral substances and are thought to contribute to the regulation of blood flow through the glomerulus. Mesangial hyperplasia and increased mesangial matrix occur in a number of glomerular diseases. The nephron tubule, called the proximal convoluted tubule, is coiled and drains the Bowman capsule
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