What major pathologic and structural changes are associated with asbestosis?

1. Fibrocalcific pleural plaques
2. Excessive bronchial secretions
3. Bronchospasm
4. Mediastinal shift
a. 1, 3
b. 2, 4
c. 1, 2, 3
d. 1, 2, 3, 4


C
Fibrocalcific pleural plaques, bronchospasm, and excessive bronchial secretions are among the pathologic and structural changes associated with asbestosis.

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