An infant with a congenital heart defect is to receive a dose of palivizumab (Synagis). What is the purpose of this?
a. Prevent RSV infection.
b. Prevent secondary bacterial infection.
c. Decrease toxicity of antiviral agents.
d. Make isolation of infant with RSV unnecessary.
ANS: A
The only product available in the United States for prevention of RSV is palivizumab, a humanized mouse monoclonal antibody, which is given once every 30 days (15 mg/kg) between November and March. It is given to high-risk infants, which includes an infant with a congenital heart defect.
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