The therapeutic level of theophylline is directly related to the blood levels achieved from the administration of the medication on a regular schedule. Which factors affect therapeutic levels? (Select all that apply.)
a. Variance in rates of absorption
b. Fluid intake
c. Metabolism
d. Age of the patient
e. Elimination
ANS: A, C, D, E
Factors affecting therapeutic theophylline blood levels are variance in rate of absorption, metabolism, and elimination of the drug; differing levels of theophylline in each product; and the patient's age.
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