An 88-year-old woman has developed syncope (fainting) since an antihypertensive agent was added to her medication regime. The development of syncope may be related to which of the following physiologic processes?
A) Interaction of other medications
B) Ingestion of herbal supplements
C) Diminished excretion of the medication
D) Increased metabolism of the medication
C
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Adverse effects of medications in an elderly patient are likely because of physiologic changes associated with aging, pathologic changes due to disease processes, multiple drugs for acute and chronic disorders, impaired memory and cognition, and difficulty in complying with drug orders. The question does not address the interaction of other medications. The question does not identify any herbal supplements. Based on physiologic alterations, the patient will not have increased metabolism of the medication.
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