An important mechanism that affects varying drug action and metabolism is the:
A. GI tract effect
B. intestinal effect
C. first-pass effect
D. toxic drug action
c
Rationale: The first-pass effect greatly affects drug action and metabolism. Because the GI tract includes the stomach and intestines, it is not a focused answer; the intestines are simply part of the GI tract; and toxic drug action is just a type of drug action and thus is not a correct choice.
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