Acetylcholine (ACh) may excite postsynaptic neurons in the CNS; however, it may inhibit some postsynaptic neurons in the PNS. Explain how acetylcholine can be both excitatory and inhibitory
What will be an ideal response?
Acetylcholine can have an excitatory effect if it induces an EPSP when it binds a receptor. An inhibitory effect results if it produces an IPSP in the postsynaptic neuron. The type of receptor to which the neurotransmitter ACh binds determines the postsynaptic response.
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