You are investigating a particular cell type, and you notice that a protein normally found in the lysosome ends up being secreted from the cell. This appears to be the only thing wrong with these cells
Of the following conditions, which is the most likely cause of this defect in these cells?
A. The lysosome leaks the protein out of the
cell.
B. The signal sequence on the lysosomal
protein is defective.
C. Transport vesicles responsible for sorting
in the cell are defective.
D. The pH of the lysosome is not low enough
for the protein to remain in it.
Answer Key: B
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