Which of the following would be an unexpected finding in homozygous b0-thalassemia?

a. Decreased reticulocyte production index
b. Normal Hb F
c. Bone marrow erythroid hyperplasia
d. Severe anemia


ANS: B
The primary hemoglobin in homozygous b0-thalassemia is Hb F, with the remainder being Hb A2. Because no b globin chains are made, no Hb A exists.

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