In the face of chronically elevated levels of CO2, what happens to the response mediated by the central chemoreceptors?
a. It is accentuated or increased.
b. It is muted or decreased.
c. There is no change in the response.
d. There is no way to predict the body's re-sponse.
ANS: B
The stimulatory effect of chronically high CO2 on the central chemoreceptors gradually declines over 1 or 2 days, because the kidneys retain bicarbonate ions in response to respiratory acidosis, bringing the blood pH level back toward normal.
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