What might happen if a functional copy of the TP53 gene is not present in a cell?
a) the cell may make no p21 inhibitory protein, preventing the cell from passing the G1 checkpoint and no Bax protein, which would prevent the cell from initiation apoptosis
b) all of the choices are correct
c) the cell proceeds to S phase before it is ready and before DNA repairs are completed
d) abnormal cells with the potential to become malignant are produced
Ans: b) all of the choices are correct
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Denaturation of protein X yields two subunits, A (MW 8,000) and B (MW 20,000). In order to understand the quaternary structure, a crosslinking experiment was performed with cell extracts
Analysis of the crosslinking products by SDS-PAGE showed four bands of the following molecular weights: 7,800, 19,500, 39,000, and 48,000 . This data suggests that protein X functions in vivo as: A. a dimer. B. a trimer. C. a tetramer. D The results are inconclusive.
The phenotype in homozygous dominant individuals affected with an autosomal genetic disorder is often more severe than the ____________________ phenotype
Fill in the blank(s) with correct word
Retinal progenitor cells give rise to all of the following, EXCEPT
A. Amacrine Cells B. Bipolar Cells C. Ganglion Cells D. Photoreceptors E. Retinal Pigment Epithelium (RPE)
Which of the following is not considered a lymphoid organ or tissue?
A) Thymus B) Bone marrow C) Heart D) Spleen E) Lymph node