From the sequencing of the human genome, we believe that there are approximately 21,000 protein-coding genes in the genome, of which 1500–3000 are transcription factors

If every gene has a tissue-specific and signal-dependent transcription pattern, how can such a small number of transcriptional regulatory proteins generate a much larger set of transcriptional patterns?


Transcription regulators are generally used in combinations, thereby increasing the possible regulatory repertoire of gene expression with a limited number of proteins.

Biology & Microbiology

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Biology & Microbiology