The nurse caring for a client diagnosed with syndrome of inappropriate antidiuretic hormone (SIADH) will prepare to administer which medications to this client?
Standard Text: Select all that apply.
1. Furosemide (Lasix)
2. Conivaptan (Viprostol)
3. Demeclocycline (Declomycin)
4. Tetracycline
5. Bleomycin
Correct Answer: 1,2,3
Rationale 1: This medication is used to remove excess fluid caused by the disorder.
Rationale 2: This medication promotes renal water excretion in clients with SIADH.
Rationale 3: This medication is used off-label to treat SIADH because it causes diuresis through inhibiting ADH-induced water reabsorption in the tubules and collecting ducts of the kidneys.
Rationale 4: This medication is not used in the treatment of SIADH.
Rationale 5: This medication is not used in the treatment of SIADH.
Global Rationale: Diuretic therapy, conivaptan (promotes renal water excretion), and demeclocycline (inhibits ADH-induced water reabsorption) are all useful in the treatment of SIADH. Tetracyline and bleomycin are indicated for use in treatment of SIADH.
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