Two proteins, Rag-1 and Rag-2, catalyze VDJ recombination. What is the likely outcome of a deletion of the Rag genes?
A. Mild susceptibility to infection due to T cell defects
B. Severe combined immunodeficiency (SCID) of both B and T cells
C. Increased antibody diversity from B cells
D. Increased resistance to infection due to enhanced B and T cell function
Answer: B
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