A nurse is taking care of a diabetic patient who is 2 days postoperative after a total knee replacement
The patient has been requesting morphine sulfate frequently for pain, which she rates as 7 or 8 on a scale of 0 to 10. Her vital signs are T–98.9° F, P–88/minute, R–12/minute, and BP–136/88. Which of the following classes of medications should the nurse be most concerned about giving concurrently with morphine sulfate?
a. Antihypertensives
b. Benzodiazepines
c. Antihistamines
d. Antidiabetics
ANS: B
Concurrent use of benzodiazepines and morphine sulfate puts the patient at risk for respiratory depression, and the patient's respirations currently are just at the low end of normal at 12/minute.
The patient's blood pressure is high but not considered hypertensive, therefore antihypertensives would not be indicated at this time. Her blood pressure may be elevated secondary to her pain. If applicable, giving antihypertensives and morphine sulfate would not be contraindicated.
Antihistamines, if needed, would not be contraindicated in a patient who also is receiving morphine sulfate.
An antidiabetic agent would have no drug-to-drug interaction with morphine sulfate.
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