Celiac sprue in the adult can lead to systemic problems. Arrange the pathophysical events of this in order of their appearance. (Separate letters by a comma and space as follows: A, B, C, D)
a. Malabsorption
b. Weight loss/vitamin deficiency
c. Systemic involvement
d. Diarrhea
e. Ingestion of gluten
f. Destruction of villi in the small intestine
ANS:
E, F, A, D, B, C
The ingestion of gluten in the small intestine damages the villi, which leads to malabsorption and diarrhea. Weight loss and vitamin deficiency, which occur from altered nutrition, can expand into systemic involvement.
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