An instructor is developing a plan for a class of nursing students on various skin disorders. When describing urticaria, what would the instructor include?
A) It is a type IV hypersensitivity reaction.
B) Histamine release leads to vasodilation.
C) Wheals appear first followed by erythema.
D) The nonpruritic rash blanches with pressure.
Ans: B
Urticaria is a type I hypersensitivity reaction caused by an immunologically mediated antigen–antibody response of histamine release from the mast cells. Vasodilation and increased vascular permeability result, leading to erythema and then wheals. The rash is pruritic and blanches with pressure.
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