Imagine a situation in which an individual who has a latent cytomegalovirus (CMV) infection receives a hematopoietic stem-cell transplant. Which of the following is likely to occur?

Question

a. The memory T cells present at the time of transplantation would inhibit activation of newly generated naive T cells.
b. The CMV viral load would increase exponentially, overcoming the host and causing death.
c. The transplant-derived naive T cells would be activated and give rise to memory T cells that would persist and control viral load.
d. There would be a rapid increase in CMV viral load and expansion of T cells bearing CD45RA.

Answer 1

C