Why would some cells, such as erythrocytes, express GLUT1, but other cells, such as liver cells, express GLUT2, which has a different kinetic relationship between v (rate of diffusion) and ?[S] (solute concentration gradient)?

What will be an ideal response?


Answer: The v vs [S] kinetic relationship for GLUT1 enables it to efficiently import glucose from the bloodstream into the cell to use for cellular activities but not to export glucose. The v vs [S] kinetic relationship for GLUT2 enables it to import glucose into liver cells for storage when blood sugar concentration is high and to export glucose through the same transporter when blood sugar level drops to maintain blood sugar level homeostasis in the range of 3.6–5.0 mM.

Biology & Microbiology

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