Which co-morbidity commonly associated with type 2 diabetes mellitus enhances the develop-ment of the microvascular complications of diabetes mellitus?

a. Hyperlipidemia
b. Hypothyroidism
c. Venous insuffi-ciency
d. Chronic constipa-tion


A
Hyperlipidemia, a condition commonly associated with type 2 diabetes mellitus, accelerates the development of microvascular complications of diabetes mellitus because high serum, low-density lipoproteins contribute to the formation of atherosclerotic plaque. The plaque first accumulates in the smallest arteries, causing complications of diabetes mellitus including peri-pheral arterial disease, retinopathy, and nephropathy. Hypothyroidism, venous insufficiency, and chronic constipation are not associated with type 2 diabetes mellitus.

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