Which of the following is required for formation of the open complex of replication initiation?

A. binding of DnaB helicase to single strands of the replication bubble
B. binding of DnaC to the four 9-mer consensus sequences, which destabilizes the AT-rich repeat sequences
C. binding of DnaA to the four 9-mer consensus sequences, which destabilizes the AT-rich repeat sequences
D. DnaA/DnaC/ATP complex loads DnaA onto the origin and ATP hydrolysis allows release of the DnaC protein
E. oligomerization of the HU protein upon binding the origin, and wraping of the DNA around the oligomer


C

Biology & Microbiology

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