Urine tests have been ordered to evaluate the adrenal function of a client. Which of the following tests is the most diagnostic urine test of adrenal medulla function?
A) Clonidine suppression test
B) Urinary metanephrine
C) 24-hour urine specimen
D) Histamine administration
B
Feedback:
Urinary metanephrine is the most diagnostic urine test of adrenal medulla function. A 24-hour urine specimen may be collected to determine vanillylmandelic acid (VMA), a metabolite of catecholamines. A clonidine suppression test can help determine pheochromocytoma, a catecholamine-secreting adrenal tumor. A somewhat risky test involves histamine administration, which produces a hypertensive crisis when the client has pheochromocytoma.
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