The nurse is caring for a client who is prescribed digoxin (Lanoxin) and diltiazem (Cardizem). The nurse recognizes which finding as representing an adverse interaction of this combination of drugs?
1. Peripheral edema
2. Headache
3. Hypertension
4. Bradycardia
Correct Answer: 4
Rationale 1: Peripheral edema is not an adverse reaction to the combination of diltiazem (Cardizem) and digoxin (Lanoxin).
Rationale 2: Headache is not a serious adverse effect associated with either drug.
Rationale 3: Hypertension is not a consequence of the interaction of diltiazem (Cardizem) and digoxin (Lanoxin).
Rationale 4: An adverse effect of the combination of diltiazem (Cardizem) and digoxin (Lanoxin) is a rise in serum digoxin concentration and risk of digoxin toxicity. Bradycardia is one sign of digoxin toxicity.
Global Rationale: An adverse effect of the combination of diltiazem (Cardizem) and digoxin (Lanoxin) is a rise in serum digoxin concentration and risk of digoxin toxicity. Bradycardia is one sign of digoxin toxicity. Peripheral edema is not an adverse reaction to the combination of diltiazem (Cardizem) and digoxin (Lanoxin). Headache is not a serious adverse effect associated with either drug. Hypertension is not a consequence of the interaction of diltiazem (Cardizem) and digoxin (Lanoxin).
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True False