A nurse is providing teaching to a nursing student about to care for a woman with irritable bowel syndrome with diarrhea (IBS-D) who is receiving alosetron [Lotronex]. Which statement by the student indicates a need for further teaching?
a. "I should evaluate the patient's abdomen for distension and bowel sounds."
b. "Patients with diverticulitis and IBS-C may take this drug."
c. "This drug can cause ischemic colitis in some patients."
d. "This drug is given only to women with severe IBS-D."
B
Alosetron is approved for use in women only with diarrhea-predominant IBS; it is contraindi-cated in patients with diverticulitis. Constipation can be a severe adverse effect, so patients should be assessed for signs of constipation, such as abdominal distension and diminished bowel sounds. Alosetron can cause ischemic colitis. Alosetron is approved for use in women with IBS-D regardless of the severity of the disease.
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