A patient who is hospitalized for an acute gout attack has received several doses of hourly oral colchicine but still reports moderate to severe pain. As the nurse prepares to administer the next dose, the patient begins vomiting
What will the nurse do? a. Contact the provider to discuss giving a lower dose of colchicine.
b. Hold the medication and notify the pre-scriber.
c. Explain that this is a common side effect that will soon stop.
d. Request an order for an antiemetic so that the next dose of colchicine may be given.
B
Colchicine should be discontinued immediately, regardless of the status of the joint pain, if ga-strointestinal (GI) symptoms occur. The patient's symptoms indicate injury to the GI endothe-lium. Once damage begins to occur, lowering the dose is not indicated. GI toxicity will not abate over time. An antiemetic may be useful for stopping the vomiting; however, continued adminis-tration of the drug can lead to further damage to the GI endothelium.
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