A client with hairy cell leukemia complains of flu-like symptoms including fever, chill, dizziness, and fatigue during the first few weeks of chemotherapy. Which medication on the client's MAR does the nurse anticipate is causing these symptoms?
1. Paclitaxel (Taxol)
2. Letrozole (Femara)
3. Daunorubicin (Cerubidine)
4. Interferon alfa-2 (Roferon A)
Correct Answer: 4
Rationale 1: Paclitaxel (Taxol) is incorrect because paclitaxel (Taxol) is a plant extract used to treat ovarian and breast cancers.
Rationale 2: Letrozole (Femara) is incorrect because letrozole (Femara) is a hormone blocker used to treat advanced breast cancer.
Rationale 3: Daunorubicin (Cerubidine) is incorrect because daunorubicin (Cerubidine) is a antitumor antibiotic used to treat Kaposi's sarcoma.
Rationale 4: Interferon alfa-2 (Roferon A) is used to treat hairy cell leukemia and Kaposi's sarcoma, and is a biologic response modifier. The most common side effect of biologic response modifiers is a flu-like syndrome of fever, chills, dizziness, and fatigue that usually diminishes as therapy progresses.
Global Rationale: Interferon alfa-2 (Roferon A) is used to treat hairy cell leukemia and Kaposi's sarcoma, and is a biologic response modifier. The most common side effect of biologic response modifiers is a flu-like syndrome of fever, chills, dizziness, and fatigue that usually diminishes as therapy progresses. Paclitaxel (Taxol) is incorrect because paclitaxel (Taxol) is a plant extract used to treat ovarian and breast cancers. Letrozole (Femara) is incorrect because letrozole (Femara) is a hormone blocker used to treat advanced breast cancer. Daunorubicin (Cerubidine) is incorrect because daunorubicin (Cerubidine) is a antitumor antibiotic used to treat Kaposi's sarcoma.
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