You are treating a patient suffering from severe anaphylaxis. Which of the following dosages of epinephrine would you be likely to administer?

a. Epinephrine 1:1000, 0.3–0.5 mg IM
b. Epinephrine 1:1000, 0.3–0.5 mg IV
c. Epinephrine 1:10,000, 0.3–0.5 mg IV
d. Epinephrine 1:10,000, 0.05–0.1 mg IV


d
Rationale: In cases of severe anaphylaxis, the dosage of epinephrine 1:10,000 should be 0.05–0.1 mg intravenously. This is 5–10% of the normal dosage used in cardiac arrest. It may need to be administered every 3–5 minutes due to the half-life.

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