A patient receiving isoniazid (INH) and rifampin (Rifadin) has a decreased urinary output and decreased sensation in his great toes. Which laboratory values should be assessed?
A) Hematocrit and hemoglobin
B) ALT and AST
C) Urine culture and sensitivity
D) Erythrocyte count and differential
B
Feedback:
Hepatotoxicity and peripheral neuropathy are important adverse effects of isoniazid and rifampin. The ALT/AST will assess liver function. The hematocrit and hemoglobin are not indicated with the described symptoms. Erythrocyte count and differential are not indicated with these symptoms.
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