A client is receiving heparin (Hep-Lock) therapy, and serious hemorrhage occurs. Which medication should the nurse administer to reverse the effects of heparin (Hep-Lock)?
1. Vitamin K
2. Desirudin (Iprivask)
3. Potassium chloride
4. Protamine sulfate
4
Rationale 1: Vitamin K reverses the effect of warfarin (Coumadin).
Rationale 2: Desirudin (Iprivask) is a newer antithrombin medication that is given subcutaneously 15 minutes prior to hip replacement surgery for prophylaxis of DVT.
Rationale 3: Potassium chloride does not reverse the effects of heparin.
Rationale 4: If serious hemorrhage occurs, a specific blocker, protamine sulfate, may be administered to neutralize the anticoagulant activity of heparin. Protamine sulfate has an onset time of 5 minutes, and is also a blocker of the LMWHs.
Global Rationale: If serious hemorrhage occurs, a specific blocker, protamine sulfate, may be administered to neutralize the anticoagulant activity of heparin. Protamine sulfate is a blocker of the LMWHs. Vitamin K reverses the effect of warfarin (Coumadin). Desirudin (Iprivask) is a newer antithrombin medication that is given subcutaneously 15 minutes prior to hip replacement surgery for prophylaxis of DVT. Potassium chloride does not reverse the effects of heparin.
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