A 72-year-old widow has just returned home after 2 weeks in the hospital after a fall. She lives alone and is visited weekly by her son. She takes digoxin, hydrochlorothiazide, and an antihypertensive drug
She also has a prescription for diazepam (Valium) as needed for moderate to severe anxiety. When the visiting nurse stopped by 2 days after discharge, he found the woman confused and disoriented, with an unsteady gait. The patient asks him who the small people are who have been living in her house. The patient had not evidenced any of these symptoms at the time of discharge. Vital signs were unremarkable except for bradycardia. The nurse correctly deduces that the most likely cause for the changes seen in the patient is: a. delirium.
b. dementia.
c. amnestic syndrome.
d. drug toxicity.
D
Drug toxicity can cause a number of mental status changes, particularly in an elderly or medically fragile person. Digoxin toxicity can cause a delirium-like presentation that includes hallucinations (e.g., the small people the patient asked about in this case), and excess valium ingestion can cause central nervous system depression and confusion. In addition to memory disturbances and disorientation, delirium is characterized by an abrupt onset of fluctuating levels of awareness, clouded and/or fluctuating consciousness, and perceptual disturbances, which are not evident in this case. Dementia has a gradual onset, contrary to the acute nature of this patient's symptoms. Amnestic disorder involves memory impairment without other cognitive problems.
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