A nurse is caring for a patient on heparin for a deep vein thrombosis (DVT) and realizes that the patient has received an overdose of the medication. When contacting the physician, what orders does the nurse anticipate?
A.
Laboratory draw for PT/INR; administer protamine sulfate.
B.
Laboratory draw for PT/INR; administer vitamin K.
C.
Laboratory draw for aPTT; administer protamine sulfate.
D.
Laboratory draw for aPTT; administer vitamin K.
ANS: C
Heparin therapy is monitored with the aPTT (activated partial thromboplastin time). The antidote for heparin is protamine sulfate. PT (prothrombin time) and INR (international normalized ratio) are used to monitor warfarin sodium therapy, although in many places INR is totally replacing the PT. Vitamin K is the antidote to warfarin.
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