A patient is taking calcium for the treatment of hypocalcemia. The nurse is reviewing the medication administration record. Which medication, when administered concurrently, would reduce the absorption of oral calcium?
a. Tetracycline
b. Prednisone
c. Chlorothiazide (Diuril)
d. Levothyroxine (Synthroid)
ANS: B
Glucocorticoids, such as prednisone, reduce the absorption of oral calcium.
Calcium reduces absorption of tetracycline, not the reverse. These drugs should be administered at least 1 hour apart.
Thiazide diuretics reduce renal calcium excretion and may cause hypercalcemia. The drugs can be administered concurrently.
Calcium reduces absorption of thyroid hormone, not the reverse, therefore they should be taken several hours apart.
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