Explain why inulin is an ideal choice to measure renal clearance and the glomerular filtration rate (GFR)

What will be an ideal response?


Inulin, a plant polysaccharide, is filtered by the kidneys but it is neither reabsorbed nor secreted by the renal tubule or collecting system. For a substance to provide an accurate view of the glomerular filtration rate (GFR), the substance should be completely filtered yet neither reabsorbed nor secreted. If a substance is secreted by the renal tubules, the substance will show a greater renal clearance than GFR whereas substances that are reabsorbed will show a lower renal clearance than GFR.

Anatomy & Physiology

You might also like to view...

Which layer of the heart wall consists of cardiac muscle tissue?

a) Epicardium b) Pericardium c) Myocardium d) Endocardium e) Hypocardium

Anatomy & Physiology

The last part of the renal tubule is the

A) proximal convoluted tubule. B) nephron loop. C) glomerulus. D) glomerular capsule. E) distal convoluted tubule.

Anatomy & Physiology

Tears are secreted by?

A) ?conjunctiva. B) ?lacrimal glands. C) ?sclera. D) ?choroid.

Anatomy & Physiology

Which of the following is associated with the "flight-or-fight" reaction?

A. Reduced urinary output B. Increased gastric motility C. Glycogen synthesis D. Reduced heart rate E. Pupillary constriction

Anatomy & Physiology