A nurse is caring for four clients who are receiving clozapine, lithium, fluoxetine, and venlafaxine,
respectively.
In which client should the nurse be most alert for alterations in cardiac or cerebral
electrical conductivity and fluid and electrolyte imbalance?
a. The client receiving lithium (Lithobid)
b. The client receiving clozapine (Clozaril)
c. The client receiving fluoxetine (Prozac)
d. The client receiving venlafaxine (Effexor)
ANS: A
Lithium is known to alter electrical conductivity, producing cardiac dysrhythmias, tremor,
convulsions, polyuria, edema, and other symptoms of fluid and electrolyte imbalance. Option B:
Clients receiving clozapine should be monitored for agranulocytosis. Option C: Clients receiving
fluoxetine should be monitored for acetylcholine block. Option D: Clients receiving venlafaxine
should be monitored for heightened feelings of anxiety.
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