Which of the following drugs inhibits the synthesis of thyroid hormones and reduces peripheral conversion of T4 to the more potent T3?
a. Liotrix (Thyrolar)
b. Levothyroxine (Synthroid)
c. Methimazole (Tapazole)
d. Propylthiouracil (PTU)
ANS: D
PTU blocks the synthesis of thyroid hormones and also reduces peripheral conversion of T4 to T3. By inhibiting the synthesis of thyroid hormones, PTU reduces the signs and symptoms of hyper-thyroidism.
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