The nurse caring for a client with renal failure will question the use of a usual dose of which medication?
1. Digoxin (Lanoxin)
2. Cholestyramine (Questran)
3. Fluvastatin (Lescol)
4. Benzylpenicillin (penicillin G)
Correct Answer: 1
Rationale 1: Digoxin has a narrow therapeutic index and is renally excreted. The dose should be reduced.
Rationale 2: Cholestyramine is not systemically absorbed and thus is not renally excreted.
Rationale 3: Fluvastatin undergoes greater than 95% hepatic excretion.
Rationale 4: Benzylpenicillin is not contraindicated for clients with renal failure.
Global Rationale: Digoxin has a narrow therapeutic index and is renally excreted. The dose should be reduced. Cholestyramine is not systemically absorbed and thus is not renally excreted. Fluvastatin undergoes greater than 95% hepatic excretion. Benzylpenicillin is not contraindicated for clients with renal failure.
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