Which of the following tests can confirm a paroxysmal nocturnal hemoglobinuria diagnosis in a patient?

a. Sucrose hemolysis test (sugar water test)
b. Reticulocyte count
c. Ham test (acidified serum lysis test)
d. Flow cytometry for cell surface markers


ANS: D
The reticulocyte count is elevated in all hemolytic anemias at the time of hemolysis (unless an aplastic crisis is present). Of the other procedures listed only flow cytometry is sensitive enough to be useful for the diagnosis of paroxysmal nocturnal hemoglobinuria. The sucrose hemolysis and Ham tests have been replaced by flow cytometry.

Health Professions

You might also like to view...

As you approach a female patient, she appears unresponsive with her arms and legs jerking violently. On the prehospital care report, you would document that the patient was found in what phase of a generalized seizure?

A) Tonic B) Absence C) Syncopal D) Clonic

Health Professions

What is the MOST common complication associated with a tracheostomy tube?

A) Air leakage around the cuff B) Tube dislodgement C) Mucus obstructing the tube D) Infection at the stoma

Health Professions

Paramedics use the findings of the two "mortis" to help confirm biological death.

Answer the following statement true (T) or false (F)

Health Professions

How is the image receptor positioned to expose an occlusal radiograph?

What will be an ideal response?

Health Professions